caz 1

[originaltup]

A 41-year-old woman has an abdominal CT scan performed because of a family history of renal neoplasms and seizures. A 5 cm right upper renal mass is present that is solid but heterogenous. A partial nephrectomy is performed. Microscopically, the mass is composed of adipose tissue with admixtures of smooth muscle and thick-walled blood vessels. Which of the following abnormalities of the nervous system is most likely to be present:

A Encephalocele

B Berry aneurysm

C Auditory nerve deafness

D Vasculitis

E Cerebral cortical tubers

[originaltup]

Raspuns corect: E

Are scleroza tuberoasa, care se asociaza cu angiomiolipoame renale (concordant cu aspectul biopsiei) si rabdomioame cardiace.
De asemenea mai sunt proliferari hamartomatoase ale astrocitelor care pot duce la convulsii, retard mental, leziuni tegumentare (adenoma sebaceum, fibroame periunghiale).